These faculty are also members of the Chemical and Systems Biology Training Program and can serve as mentors for Chemical and Systems Biology/Molecular Pharmacology graduate students.

	Gilbert Chu, M.D., Ph.D. Department of Medicine--Oncology Research Interest: Our goal is to understand how DNA double-strand breaks are repaired by nonhomologous end-joining, a pathway that repairs breaks created by ionizing radiation and V(D)J recombination. A second goal is to predict toxicity from radiation therapy by measuring transcriptional responses to ionizing radiation on microarrays and developing methods for analyzing the data.
	Gerald R. Crabtree, M.D. Professor of Pathology and Developmental Biology Howard Hughes Medical Institute Investigator
	Ricardo Dolmetsch,Ph.D Department of Neurobiology Research Interest: Our lab studies how experience changes the structure and function of neurons and neuronal circuits. We have three major areas of interest: We are interested in how calcium channels control neuronal function by altering the cell biological properties of neurons like differentiation and synapse formation. We are also interested in autism, particularly in developing cellular and animal models of the disease. Finally we are interested in developing new technologies to study neuronal signaling in live cells.
	Amato J. Giaccia, Ph.D. Department of Radiation Oncology -- Radiation Biology Research Interest: My lab focuses on the cellular response to stresses found in the tumor microenvironment, especially low oxygen conditions (tumor hypoxia). Our long-term goal is to identify and characterize the molecular and physiological changes induced by the tumor microenvironment that influence the malignant progression of transformed cells.
	Dan Herschlag , Ph.D. Department of Biochemistry Research interest: My lab uses biochemical and biophysical approaches to study biological catalysis by RNA and proteins, with the general goal of understanding how RNA and protein enzymes achieve their enormous rate enhancements and exquisite specificity. We study RNA folding in an effort to uncover the fundamental physical behaviors of biomolecules, and we investigate RNA processing at the genomic level and study the behavior of RNA molecules in vivo.
	Peter K. Jackson, Ph.D. Department of Pathology [currently on leave]
	Karla A. Kirkegaard, Ph.D. Department of Microbiology and Immunology
	Brian K. Kobilka, M.D. Department of Molecular and Cellular Physiology Howard Hughes Medical Institute Investigator Research Interest: My lab studies the structure and mechanism of action of G protein coupled receptors using the beta adrenergic receptor as our primary model system.
	Richard S. Lewis, Ph.D. Department of Molecular and Cellular Physiology Research interest:   We seek to understand the mechanisms of calcium signaling in T lymphocytes, including the control of store-operated Ca 2+ channels and the informative role of Ca 2+ signals during development using 2-photon microscopy of living tissue.
	Vijay Pande, Ph.D. Department of Molecular and Cellular Physiology Research interest: My labs interests revolve around the kinetics and thermodynamics of biomolecules, addressed via a combination of simulation, theory, and experiment. More specifically, we have concentrated on biomoelcular conformational change involved in protein folding, RNA folding, protein-ligand binding, and lipid vesicle fusion.
	Joseph D. Puglisi, Ph.D. Department of Structural Biology